1.更新系统
yum update
2.安装必要的相关库
yum install gcc gcc-c++ bison pkgconfig glib2-devel gettext make libpng-devel libjpeg-devel libtiff-devel libexif-devel giflib-devel libX11-devel freetype-devel fontconfig-devel cairo-devel httpd httpd-devel
3.安装 libgdiplus
cd /usr/local/src/
wget http://download.mono-project.com/sources/libgdiplus/libgdiplus-2.10.tar.bz2
tar -jxvf libgdiplus-2.10.tar.bz2
cd libgdiplus-2.10
./configure –prefix=/opt/mono
make
make install
echo “/opt/mono/lib” > /etc/ld.so.conf.d/mono.conf
ldconfig
4.安装 mono
cd /usr/local/src/
wget http://download.mono-project.com/sources/mono/mono-2.10.8.tar.bz2
tar -jxvf mono-2.10.8.tar.bz2
cd mono-2.10.8
./configure –prefix=/opt/mono
make
漫长的等待…….
make install
echo export PKG_CONFIG_PATH=/opt/mono/lib/pkgconfig:$PKG_CONFIG_PATH>>~/.bash_profile
echo export LD_LIBRARY_PATH=/opt/mono/lib:$LD_LIBRARY_PATH>>~/.bash_profile
echo export PATH=/opt/mono/bin:$PATH>>~/.bash_profile
source ~/.bash_profile
输入 mono -V 如有mono版本信息,则安装成功.
5.安装mono xsp-2.10
cd /usr/local/src/
wget http://download.mono-project.com/sources/xsp/xsp-2.10.tar.bz2
tar jxvf xsp-2.10.tar.bz2
cd xsp-2.10
./configure -prefix=/opt/mono
make
make install
6.安装mod_mono-2.10
cd /usr/local/src/
wget http://download.mono-project.com/sources/mod\_mono/mod\_mono-2.10.tar.bz2
tar jxvf mod_mono-2.10.tar.bz2
cd mod_mono-2.10
./configure -prefix=/opt/mono
make;
make install
mod_mono配置：
cp /etc/httpd/conf/mod_mono.conf /etc/httpd/conf.d/mod_mono.conf
在mod_mono.conf中加入如下配置
MonoServerPath /opt/mono/bin/mod-mono-server4
修改/etc/profile,在末端添加
MONO_HOME=/opt/mono
PATH=$MONO_HOME/bin:$PATH
CLASSPATH=.:$MONO_HOME/lib/
export MONO_HOME
export PATH
export CLASSPATH
转自：http://www.cnblogs.com/aquilahkj/archive/2011/11/03/2234380.html